Herb-Jyotishmati

Jyotishmati
(Celastrus paniculatus)

Part Used: Seed

Habitat:

Introduction:
C. paniculatus has a remarkable therapeutic value. This plant has an important role in enhancing cognitive function and the natural luminosity (jyoti) of the mind (mati).

Mechanism of Action:
Mechanism of anti-inflammatory action of C. paniculatus may be related to inhibiton of prostaglandin synthesis and the release of IL-1β.
Kulkarni, et al.: Jyotishmati seeds in pain and infl ammation; Journal of Ayurveda & Integrative Medicine

The antioxidant effect of C. paniculatus is due to its decreasing effect in the brain levels of malodialdehyde, with simultaneous significant increase in levels of glutathione and catalase.
International Journal of Recent Advances in Pharmaceutical Research, January 2011; 1: 19-24

Medicinal Uses:
Learning and memory – This improves learning and memorizing capacity. It selectively reverses the impairment in spatial (about one’s environment) memory produced by acute central muscarinic receptor blockade, but is not related to an anticholinesterase-like action.

Antioxidant Effect - This has a free radical scavenging capacity and protects DNA cleavage due to the protective effect on cytotoxicity and DNA damage.
Int J Pharm Bio Sci 2012 July; 3(3): (P) 290 - 303

Analgesic and anti-inflammatory Effect – Celastrus paniculatus has significant analgesic (pain reducing) and anti-inflammatroy activity.
Kulkarni, et al.: Jyotishmati seeds in pain and infl ammation; Journal of Ayurveda & Integrative Medicine

Clinical Studies:

NA…..

Conclusion:

Jyotishmati is a herb which is meant to enhance the brain capacity to work efficiently, hence considered as a brain tonic. Its name also suggests that it was being used to increase mind power since ancient time.