Part Used: Stem
The plant is used in ayurvedic, "Rasayanas" to improve the immune system and the body resistance against infections.
It is called as guduchi in Sanskrit and Amrita or Giloya in hindi. The term ‘Amrita’ is attributed to this herb in recognition of its ability to impart youthfulness, vitality and longevity to its patron.
The origin of guduchi goes back to Ramayan era, the kidnapping of Sita and the war that followed, in which Ram led the army of monkeys to fight the all-powerful demon king Ravan. In this war, the proud of his strength, Ravan, the foe of devtas, was killed. Indra, the thousand eyed and the chief of Devtas, was very pleased with Ram. So Indra sprinkled Amrit i.e. nector on all dead monkeys and brought them back to life. Wherever the Amrit drops fell on ground, due to the spilling, the Giloy (Tinospora cordifolia) was born.
Int J Res Phar Biomed Sc, Vol. 3 (1) Jan – Mar 2012
Mechanism of Action:
Antioxidant Action – T. cordifolia has free radical scavenging and antioxidant effect. This herb restores the levels of antioxidant enzymes glutathione (GSH), superoxide dismutase (SOD) and catalase in liver and kidney.
Immuno-modulatory Activity – This improves the immune system and the body resistance against infections. T. cordifolia benefits the immune system by significantly improving the bacterial clearance and intercellular bactericidal capacities of neutrophils.
Hepatoprotective – This causes a significant reduction in serum levels of SGOT, SGPT, ALP (Alkaline Phosphatase), bilirubins.
Int. J. Med. Arom. Plants, ISSN 2249-4340, Vol. 2, No. 2, pp. 340-344, June 2012
According to a clinical trial published in the Indian Journal of Gastroenterology, 1993, T. cordifolia has hepatoprotective and immunomodulatory properties. Giloy helps to normalize the phagocytic and killing capacities of neutrophils in the patients with obstructive jaundice proving its immunomodulatory action.
Indian J Gastroenterol. 1993 Jan;12(1):5-8.